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Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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1 MILLION OF US — Whalespan

Content›Video›1 MILLION OF US…

1 MILLION OF US

Bryan Johnson46m · 2024-06-16

Claims Made

54

Claims Supported

31

Support Rate

57%

Support rate

31 of 54 claims supported

31 supported23 partial / not

Claims from this content

30

✓Well SupportedBryan Johnson's structural skin biomarkers indicate a skin age 9 years younger than his chronological age.✓Well SupportedBryan Johnson publicly posts his health data, protocol, experiments, and mistakes.✓Well SupportedBryan Johnson's 30-day average RHR of 44 bpm is lower than 99.7% of the male population and lower than the range for 20-39 male athletes.✓Well SupportedBryan Johnson achieved an ideal plaque index of 24.4% and a gingival and calculus index of 0 after three years on Blueprint.Well Supported

More from Bryan Johnson

Bryan Johnson's Blueprint Rapamycin Protocol

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Reducing daily water intake to 60-80 ounces, supplemented with minerals, can improve sleep by reducing nighttime urination.

✓Well SupportedBryan Johnson has been focusing on diet, exercise, and sleep for the past two years, and is now pursuing gene therapy.

✓Well SupportedThe speaker's speed of aging is approximately half the normal rate.

◐Partially SupportedBryan Johnson and Talage meditate daily and do breathwork.

◐Partially SupportedTalage improved his heart rate variability (HRV) from the 50s to 145 by consistently exercising, avoiding junk food, and not eating close to bedtime.

✓Well SupportedA heart rate variability (HRV) of 145 is considered exceptionally high and indicative of excellent health.

◐Partially SupportedTattoos can interfere with certain skin therapies, requiring the area to be covered.

✕Not SupportedFiller injections under the eyes can mask aging and may migrate, and the preference is for genuine rejuvenation rather than covering up signs of aging.

◐Partially SupportedNicotine is a cognitive enhancer that raises attention, focus, and cognitive performance, but it also raises blood pressure and causes vasoconstriction.

◐Partially SupportedBiomarker data suggests that aging can be reversed to a significant extent.

◐Partially SupportedCovering a tattoo with tape during skin therapies may be done to avoid interaction.

✕Not SupportedColon cancer is a serious health risk that should be avoided.

◐Partially SupportedYamanaka factor reprogramming and other rejuvenation therapies are in development and showing measurable progress.

✕Not SupportedGetting up at 5:00 AM for early morning seminary after staying up until midnight doing homework negatively impacted sleep.

◐Partially SupportedThe speaker eats the same thing as Bryan Johnson, with the addition of Johnson GPT.

◐Partially SupportedPRP treatment for an ankle injury involves drawing blood, separating plasma, and re-injecting the concentrated plasma.

◐Partially SupportedBryan Johnson experienced volume loss under his eyes after reducing his calorie intake to 1950 calories during the initial phase of his Blueprint program.

◐Partially SupportedThe speaker plans to install a hyperbaric oxygen therapy system at home for daily use following the Israeli protocol of 60 sessions over 90 days.

◐Partially SupportedA pizza made with ground quinoa and vegan cheese, without flour, is acceptable to eat.

◐Partially SupportedMethylene blue has been tested but is not considered a power law intervention.

?Limited ResearchHydrogen water is being explored for its potential benefits, but its effects need to be measurable to be considered valuable.

◐Partially SupportedThe future is arriving faster than anticipated, suggesting that longevity-focused efforts are timely.

◐Partially SupportedNo-prep veneers can be applied without shaving down teeth.

◐Partially SupportedGoing to bed on time, exercising, and eating well are key longevity strategies.

◐Partially SupportedFunction Health is a recommended provider for blood work in the US for the Blueprint program.

◐Partially SupportedTo live a long life, it is important to get the basics right: sleep, diet, and exercise, and to try to avoid bad things.