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Rapamycin extends mouse lifespan 9–14%
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Understanding testosterone and why yours may be tanked — Whalespan

Content›Video›Understanding testosterone a…

Understanding testosterone and why yours may be tanked

Paul Saladino7m · 2022-03-23

Claims Made

27

Claims Supported

2

Support Rate

7%

Support rate

2 of 27 claims supported

2 supported25 partial / not

Claims from this content

24

◐Partially SupportedHuman chorionic gonadotropin (hCG) is used as a mimetic for luteinizing hormone (LH) to stimulate testosterone production by Leydig cells.◐Partially SupportedThe hypothalamus releases GnRH, which stimulates the pituitary to release LH, which then stimulates testosterone and estrogen production in the testes and ovaries.✕Not SupportedKetogenic and low-carb diets may negatively impact sex hormones by increasing sex hormone-binding globulin (SHBG), thereby reducing free hormone levels.◐Partially SupportedTestosterone can be converted to DHT via 5-alpha reductase or to estrogen derivatives via aromatase.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Estradiol has beneficial effects in men, and eliminating it with aromatase inhibitors can negatively alter lipids.

✕Not SupportedInadequate calorie consumption can lead to a decrease in testosterone levels and negatively affect thyroid function.

✕Not SupportedExcessive fiber intake can negatively affect hormone levels.

✕Not SupportedInsufficient sun exposure and low vitamin D levels can negatively affect testosterone.

✕Not SupportedInsulin resistance can disrupt hormone balance.

◐Partially SupportedElevated testosterone levels inhibit the hypothalamus and pituitary, reducing GnRH, LH, and FSH secretion.

◐Partially SupportedPregnenolone is a precursor in the steroid hormone synthesis pathway.

◐Partially SupportedThe anterior pituitary releases luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which travel to the gonads.

◐Partially SupportedSome individuals taking exogenous testosterone use aromatase inhibitors to limit estrogen conversion.

◐Partially SupportedFSH stimulates Sertoli cells in the testes to produce sperm.

◐Partially SupportedMany androgens can be converted to estrogens, often from exogenous sources.

◐Partially SupportedSteroid hormones are synthesized from a cholesterol backbone.

◐Partially SupportedCholesterol is essential for steroid hormone production.

✕Not SupportedPoor sleep quality negatively affects testosterone and other hormones.

◐Partially SupportedTestosterone, estrogens, and androgens are interconnected through simple enzymatic reactions.

◐Partially SupportedPregnenolone can be converted to mineralocorticoids like deoxycorticosterone, corticosterone, and aldosterone, which are involved in electrolyte balance.

◐Partially SupportedCorrecting calorie intake, sun exposure, sleep, nutrition, and reducing polyunsaturated fatty acids can increase testosterone levels.

✕Not SupportedNutritional deficiencies, such as in saturated fat or boron, can negatively affect hormone levels.

✕Not SupportedHigh cortisol levels can negatively impact hormones.

✕Not SupportedPolyunsaturated fatty acids, such as those found in seed oils, may negatively affect hormone levels.