Our read is that taking AG1 (Athletic Greens) is Well Supported for foundational nutritional needs and overall well-being.
Our read is that Athletic Greens is a drink containing vitamins, minerals, probiotics, and adaptogens designed to meet foundational nutritional needs and aid recovery from stress.
Experts suggest that AG1 can bolster energy, immune system, and gut microbiome, which are critical for brain function, mood, and physical performance.
However, some experts criticize AG1 for not disclosing full formulations or providing clinically relevant doses, and for its high cost relative to perceived benefits.
Andrew Huberman takes Athletic Greens twice a day. Taking AG1 once in the morning and again in the afternoon or evening is reported to cover foundational nutritional needs and improve energy levels, digestion, and sleep.
Bryan Johnson states that AG1 is a disaster within the supplement market, criticizing it for not disclosing full formulations or providing clinically relevant doses, and for only conducting one small study on subjective feelings with no measurements of clinically relevant biomarkers. Bryan Johnson also claims that the bulk of AG1's 12g scoop consists of cheap greens and emulsifiers, with high-value ingredients included only in trace amounts. Bryan Johnson and Rhonda Patrick assert that AG1 uses 'pixie dusting' by listing familiar ingredients but providing them in doses lower than those shown to be effective in clinical trials. Paul Saladino reports that AG1 scored 63/100 in a 2025 supplement test, containing 9x the recommended lead, mercury, cadmium, and natural flavoring. Rhonda Patrick states that AG1 is a multivitamin and should not replace the intake of leafy greens. Andrew Huberman notes that supplements like Athletic Greens could potentially mask signals that prompt necessary lifestyle changes.
A change in the verdict would require more comprehensive, clinically relevant studies on AG1's efficacy, particularly regarding biomarker changes and microbiome diversity, as well as greater transparency in ingredient dosages and formulations.
Benefits hold across the populations where it's been tested.
The effect size is large enough to matter clinically, not just statistically.
Benefits hold across the populations where it's been tested.
Mechanistic and trial evidence converge on a real, replicable effect.
The effect size is large enough to matter clinically, not just statistically.
The headline effect shrinks once you account for trial quality.
The headline effect shrinks once you account for trial quality.
Confounding and publication bias inflate the apparent benefit.
Animal-model results don't translate to the human protocol being recommended.
The headline effect shrinks once you account for trial quality.