Andrew Huberman· PhD
Now of course the cold itself can have some health promoting effects. It can increase brown fat thermogenesis and metabolism
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Now of course the cold itself can have some health promoting effects. It can increase brown fat thermogenesis and metabolism
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
The big effects of cold on metabolism and fat burning are going to be through two routes. One, is that if you expose yourself to cold, you have the opportunity to trigger activation of brown fat as well as to convert more beige fat into true brown fat. So you essentially create a stronger or a hotter furnace.
It can lead to increases in metabolism, brown fat stores, which are the good fat stores that you want. They're sort of like a furnace that allow you to heat yourself up, stay warm in cold environments, to reduce inflammation, to increase resilience and so forth.
Right, and beige can take on thermogenic characteristics essentially, and so you can activate beige fat so that it's thermogenic in the sense that it's burning glucose and/or fatty acids and producing heat. So the more you expose yourself to cold, the more you can brown your fat, so to speak, and therefore you can tolerate the cold for longer periods, which people do notice, and you can then have the thermogenic qualities of having more brown adipose tissue or beige, activated beige, adipose tissue.
But we know that white fat can be converted to this more metabolically active form of beige fat by deliberate cold exposure, according to the protocol I talked about earlier
This is very much the same as the mechanism that's induced when you were to, say, take a cold shower or do regular ice baths or get into cold water regularly. That, too, stimulates the conversion of white fat cells to beige and brown fat cells.
And it turns out that cold exposure to those regions of the body in particular, are going to trigger the adaptation of increased brown fat stores, which involves increases in mitochondria in those fat. Again, this is not the blubbery fat beneath the skin. This is the fat that acts as kind of an oil in the furnace that is your thermogenic properties of your body to generate heat and burn off so-called white adipose tissue elsewhere in the body.
the cold itself can have some health promoting effects it can increase Brown fat thermogenesis and Metabolism
Cold stimulates healthy brown fat.
So what is brown fat? Brown, or it's often called beige fat, is found in babies. It's typically to allow them to stay warm because they don't shiver until they're about one year of age. And what was discovered about 10 years ago at Harvard by Bruce Spiegelman and Ron Kahn, a couple of my colleagues, is that adults also have some brown fat, and they discovered this with PET scanning, and they found it mostly exists on your back in your shoulder blades. And when you get cold, it revs up, you get more of this brown fat. And this is a good thing because brown fat is extremely healthy. It revs up metabolism, it burns white fat. And we think that there are these factors, little chemicals, little proteins that get secreted out of brown fat that make the rest of the body healthy as well.
Last week I posted a video about how cold may improve metabolism by increasing brown fat.
And this is an adaptation that happens the more you expose yourself to the cold, the more you start to make brown fat. And so that that is something that is a therapeutic target for many many different researchers out there. They're trying to find a way to make a pill to increase brown atapost tissue to increase mitochondrial biogenesis in brown atapost tissue because that would be a you know weight loss mechanism, right? because you're burning more fat. Um, it's also it's it it's also associated with improving metabolic health as well.