The anti-inflammatory effects of creatine are more apparent under conditions of stress than with adequate sleep and nutrition.

“With the brain, it works in the background of stress. And what I mean by stress is sleep deprivation, psychological stress, like you have an exam, marital, I mean what whatever psychological stress, emotional stress, sleep deprivation is a big one, ner degenerative disease or anything that's compromising brain function, right? That's where creatine really shines in terms of cognitive function.”

“With the brain, it works in the background of stress. And what I mean by stress is sleep deprivation, psychological stress, like you have an exam, marital, I mean what whatever psychological stress, emotional stress, sleep deprivation is a big one, ner degenerative disease or anything that's compromising brain function, right? That's where creatine really shines in terms of cognitive function.”

“Who might benefit most? Older adults, vegetarians/vegans, and those in "metabolically stressed" states like sleep deprivation, illness, or a high training load.”

“However, these findings suggest that creatine may become a “sleep supplement” under certain conditions, particularly those involving a significant cognitive or physiological stress, for example, intensive exercise training.”

“probably the area that most people don't realize is the recovery aspects it really seems to have some anti-catabolic effects um potentially anti-inflammatory uh effects and that's interesting because it's from the aerobic Community for the longest time we never thought creatin was for endurance or aerobic type athletes and the best lines of evidence from a recovery aspect uh come from long duration aerobic exercise a marathon ultramarathon a triathlon it seems to reduce cyto so those are markers of inflammation”

“yeah there's actually a small body of search in healthy individuals young and old that say creatine without exercise actually improves muscle performance so those that i think of disuse bed rest immobilization sedentary individuals maybe they have functional mobility issues or people that don't know or have access to weight training creating by itself has been shown to”

“creatine is very cost effective but I want to make sure I'm maximizing all my abilities and the immune system especially in Canadian Winters is really heightened and uh activated and and I really have found in the last few years I'm I'm not getting flu like symptoms hopefully that's from exercise or Diet but uh who knows maybe creatine is helping because there is some anti-inflammatory effects”

“the more stressed the body is it seems to come to the rescue more so if you're a young individual adequate sleep proper nutrition you're probably not going to notice any anti-inflammatory effects it's when the body is under times of extensive exercise or trauma hypoxia — I'm sure we'll talk about the brain and sleep deprivation”

“the best lines of Defense come from Triathlon and Marathon running where the increase in these markers called cytic kinds were elevated — but creatine sort of attenuate that rise could allow the individual to recover and get back on the the track or whichever it is quicker”

“it seems to have multiple roles um anti-inflammatory anti-catabolic right um it's obviously important for producing ATP regen you know regenerating the ATP”

“if you're a young individual adequate sleep proper nutrition you're probably not going to notice any anti-inflammatory effects”

“so the anti-inflammatory role comes back there as well so you'll start to hear these two words anti-catabolic and anti-inflammatory people think of Advil or Tylenol from an anti-inflammatory but creatin seems to work some very similar in the Cox inhibitors as well and um but it seems to decrease cyto kindes um so it could be something there to consider”

“the more stressed the body is it seems to come to the rescue more so if you're a young individual adequate sleep proper nutrition you're probably not going to notice any anti-inflammatory effects it's when the body is under times of extensive exercise or trauma hypoxia um I'm sure we'll talk about the brain and sleep deprivation so whenever the body is more stressed or under more attack that's when creatine seems to come to the rescue”

“you mentioned some of the anti-inflammatory effects of creatine particularly in the context of more endurance type of training people that are perhaps running marathons or just clocking in a lot of hours of running or cycling per week”