Metformin can decrease testosterone levels in men by improving insulin sensitivity and altering ovarian function. — Whalespan
Metformin can decrease testosterone levels in men by improving insulin sensitivity and altering ovarian function.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“in PCOS this insulin resistance correlates with this testosterone production from the ovary meaning even met for alone can decrease testosterone levels based on some of the change that it has in the ovary take note men so many guys taking metformin or berberine thinking oh this is great I'm going to lower my blood sugar mimic fasting and live longer and and then these are also the same people who are riding to me go how come when I take metformin I either have headaches because I'm you know essentially hypo hypoglycemic but also their testosterone levels are are are getting crushed”
“where you might get some longevity increases but you're also pushing a lot of markers that you would might care for healthspan as well in terms of metformin potentially reducing testosterone”