The Rotterdam Study indicated a correlation between higher intake of Vitamin K2 and improved health outcomes.

“if you look at the Rotterdam study which I talked about in the book it's an epidemiology study that looked at over 4,000 people in Denmark and incidents of cardiovascular disease was significantly associated in an inverse fashion meaning that the more vitamin k2 people ate the less cardiovascular disease they had it was a very clear study and the less a Horta calcification they had”

“it's not vitamin k1 it's vitamin k2 it's the menaquinone I talked about all of this in my book the carnivore code you can pre-order the second edition now the carnivore code book calm from wherever you want to get it I talked about the huge difference between vitamin k1 which is phylloquinone found in plants and vitamin k2 specifically in the book I talk about how vitamin k2 levels the higher levels are associated with a much lower incidence of coronary artery disease and aortic calcific sclerosis calcific a artx chlorosis but not vitamin k1 meaning that those who ate the most vitamin k2 appear to be protected in population studies but intake of vitamin k1 had no effect”

“those people in the rotterdam study had the lowest rate the lowest rates of heart disease and calcific aortic sclerosis”

“the dietary intake of menoquinone is associated with a reduced risk of coronary heart disease the rotterdam study”

“phylloquinone k1 intake was not related to any outcome but increasing levels of k2 in the diet were associated with better cardiac outcomes”

“more importantly that vitamin k2 the spectrum of metaquinone specifically mk4 is probably the most bioactive one have been associated again this this is an epidemiology association in the rotterdam study with significantly decreased rates of cardiovascular disease and calcific aortic sclerosis”

“there's a large observational study called the rotterdam study and they looked at intakes of vitamin k2 and vitamin k1 in the population and they divided the population up into three groups depending on how much vitamin k2 they got we call this tertiles so the lowest group the middle group and the top group and i think the top group was”

“there's a large observational study called the rotterdam study and they looked at intakes of vitamin k2 and vitamin k1 in the population and they divided the population up into three groups depending on how much vitamin k2 they got we call this tertiles so the lowest group the middle group and the top group and i think the top group was around 35 micrograms of vitamin k2 a day and this is observational so we can't draw causative inference but it was so clear that the group that had the most vitamin k2 had the lowest rates of heart disease and the lowest rates of aortic calcific like calcific aortic sclerosis”

“the k2 is not even in the usda database and the end of that story is that vitamin k1 from plants there's no association meaning that no matter how much vitamin k1 people were getting there was no decrease in cardiovascular disease and no decrease in calcific aortic sclerosis suggesting that our body's not that good at converting k1 to k2”

“which is evidenced by the rotterdam study showing that there was no correlation between vitamin k1 intake and cardiovascular disease outcomes or calcific aortic sclerosis but vitamin k2 led to better outcomes”

“you are familiar with the rotterdam study which i can show which is an observational study but what it revealed was that those people who had the most vitamin k2 menoquinone in their diet had the best outcomes in terms of cardiovascular disease specifically cardiac events and calcific aortic sclerosis there was no correlation with vitamin k 1.”

“dietary intake of menoquinone is associated with reduced risk of coronary heart disease the rotterdam study and you can see here in the abstract the risk of coronary heart disease all-cause mortality and aortic atherosclerosis which they call calcific aortic sclerosis was studied in tertiles of energy adjusted vitamin k intake and after adjustment for age gender bmi smoking diabetes education and dietary factors the relative risk of chd mortality was reduced in the mid and upper tertiles of dietary metaquinone compared to the lower tertial relative risk was 0.73 with a confidence interval between 0.45 and 1.17 and there was a relative risk of 0.43 which had a confidence interval which did not cross one respectively in the upper tertile”

“the risk of coronary heart disease all-cause mortality and aortic atherosclerosis which they call calcific aortic sclerosis was studied in tertiles of energy adjusted vitamin k intake and after adjustment for age gender bmi smoking diabetes education and dietary factors the relative risk of chd mortality was reduced in the mid and upper tertiles of dietary medoquinone compared to the lower tertial relative risk was 0.73 with a confidence interval uh between 0.45 and 1.17 um and there was a relative risk of 0.43 which had a confidence interval which did not cross 1 respectively in the upper tertile”

“what it revealed was that those people who had the most vitamin k2 menoquinone in their diet had the best outcomes in terms of cardiovascular disease specifically cardiac events and calcific aortic sclerosis”

“what we know is that the body is pretty good at retro-converting k2 into k1 but not the reverse which is evidenced by the rotterdam study showing that there was no correlation between vitamin k1 intake and cardiovascular disease outcomes or calcific aortic sclerosis but vitamin k2 led to better outcomes”

“we know from studies like the rdam study which is observational epidemiology but if you can come up with any sort of confounding bias in that study I'm open to hear it it doesn't seem to be very confounded by either Health user bias or unhealthy user bias so I think it's a very valid observational correlation between the people that were eating the highest Teri of vitamin K2 meaning people that were eating the most vitamin K2 had the lowest rates of calcific aortic sclerosis calcification of the aortic valve and the lowest rates of cardiovascular disease”

“intake of vitamin K2 was associated with lower rates of calcification of the aortic valve and with lower rates of coronary artery disease while vitamin K1 had no association with either of those it wasn't protective at all”

“that has been associated with decreased rates of calcific aortic sclerosis calcification of aortic valve decreased rates of cardiovascular disease in the Rotterdam study”

“what the Rotterdam study also shows is that the more K2 we get as nutrient found almost exclusively in animal Foods menaquinones the lower our risks of heart disease specifically calcific aortic sclerosis and cardiovascular disease”

“the reram study is fascinating and I cite it because I get push back online when I talk about observational studies and I think that that push back is is welcomed but my response is that in these observational studies that I'm talking about I'm thinking about whether there are confounding variables and whether people are using healthy user bias or unhealthy user bias in the rdam study there there's probably no healthy user bias because people eating those Foods were not doing healthy behaviors but they still had the best longevity the lowest mortality at least the best incidence the lowest incidence of cardiovascular disease and lowest calcification of of the aortic valve”