Debunking common vegan arguments

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Paul Saladino1h 12m · 2023-02-14

Claims Made

143

Claims Supported

91

Support Rate

64%

Support rate

91 of 143 claims supported

91 supported52 partial / not

Claims from this content

110

Well SupportedThe Rotterdam Study indicated a correlation between higher intake of Vitamin K2 and improved health outcomes.Well SupportedHunter-gatherer societies offer comparable life expectancy to modern populations if individuals survive to adolescence, with a better healthspan.Well SupportedHumans have historically relied on animal foods as the primary source of protein and nutrients.Well SupportedIn Eastern epidemiological studies, higher red meat consumption in men was associated with lower rates of heart disease, and in women with lower rates of breast cancer.Well Supported

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

An animal-based diet consisting of meat, organs, fruit, honey, and raw dairy may help with gut issues or autoimmune conditions.

Well SupportedConsuming liver can significantly improve quality of life due to its dense nutrient profile.

Well SupportedMeat and organs are nutrient-rich foods essential for muscles, bones, vitality, energy, libido, and mood.

Well SupportedRestricting methionine for longevity is unnecessary; providing sufficient glycine is an alternative approach.

Well SupportedHistorical Okinawan centenarians were not vegans or vegetarians, and pork was a significant dietary component.

Well SupportedOn a carnivore diet, balance methionine from muscle meat with glycine from connective tissue to avoid biochemical imbalances.

Well SupportedRed meat intake was inversely associated with cardiovascular disease mortality in men and cancer mortality in women in Asian countries.

Well SupportedVegetarians and omnivores have similar all-cause mortality rates.

Well SupportedHeart and Soil's 'Memory and Brain', 'Beef Organs', and 'Bone Matrix' supplements have passed third-party testing for purity and are Informed Sports certified.

Well SupportedThe Hadza, a hunter-gatherer tribe, consume meat daily and are free from chronic diseases such as diabetes, obesity, autoimmune disease, depression, and cancer.

Well SupportedThe Nicoya region of Costa Rica is a longevity region where men consume more meat and animal fat than the general Costa Rican population.

Well SupportedFree-living human populations exist that are free from chronic diseases such as obesity, diabetes, cardiovascular disease, autoimmunity, cancer, depression, and dementia.

Well SupportedMany observational studies on plant-based diets are confounded by healthy user and unhealthy user bias.

Not SupportedIn vitro studies on compounds in red meat often use conditions and doses not relevant to normal human dietary intake.

Well SupportedIn animal studies, diets low in calcium were used to induce a pro-cancerous condition, and sufficient calcium prevented cancer.

Not SupportedIn individuals without hemochromatosis, heme iron is not a significant carcinogen.

Well SupportedMeat and organs are key for nutrient intake, and desiccated organ supplements are an alternative if fresh organs are unavailable.

Well SupportedVegans have a higher fracture risk due to potentially lower intake of calcium, utilizable protein, and creatine.

Well SupportedThe strong correlation between seed oil consumption and macular degeneration supports a compelling hypothesis.

Well SupportedIndividuals consuming the highest amounts of vitamin K2 from animal foods exhibited the lowest rates of cardiovascular disease.

Not SupportedStarchy foods like bread, potatoes, pasta, and rice can cause gut inflammation leading to endotoxin and downstream effects.

Not SupportedPlant proteins can create nutrient deficiencies and contain lectins that damage the gut.

Well SupportedCaloric restriction studies in monkeys were confounded by unauthorized feeding.

Partially SupportedModerate meat consumption is associated with benefits in Asian prospective cohort studies.

Partially SupportedSome people in Blue Zones eat meat, and this has been omitted from the narrative.

Not SupportedThe absence of vegetarian centenarians in Okinawa contradicts the claim that limited meat consumption is key to Blue Zone longevity.

Partially SupportedMeat and organ meats improve testosterone levels, and testicles contain bioactive androgens including testosterone.

Partially SupportedVegetarian, semi-vegetarian, or Pesco-vegetarian diets do not independently protect against all-cause mortality.

Partially SupportedCurrent hunter-gatherer tribes live as long as modern humans but with significantly better vitality and a squared morbidity curve.

Partially SupportedAdequate threonine and leucine are critical for avoiding sarcopenia.

Not SupportedThe claim that red meat is inflammatory and harmful due to specific compounds is not well-substantiated by current evidence for typical human dietary intake.

Partially SupportedIncreased consumption of animal foods by hunter-gatherers generally correlated with better health outcomes.

Partially SupportedMaple syrup is a good source of manganese and may be beneficial for humans.

Not SupportedThe widespread use of rapamycin may lead to an increase in overall infections, including tuberculosis and pulmonary infections.

Partially SupportedmTOR activation is stimulated by insulin, carbohydrates, protein, leucine, and exercise, and chronic over-activation from sources like high fructose corn syrup, late-night eating, or junk food should be avoided.

Partially SupportedMargarine intake is associated with a higher rate of cardiovascular disease.

Partially SupportedMeat and various fats in meat do not induce inflammation.

Not SupportedEpidemiological studies and observational data are insufficient to definitively prove long-term harm from animal protein.

Not SupportedThe arguments that meat negatively affects longevity are weak, and the association between plant-based diets and extended lifespan may be based on insufficient control for confounders.

Not SupportedCaloric restriction only improves metabolic function in obese humans, and there are no good human trials showing benefits for otherwise healthy individuals.

Partially SupportedEggs, milk, and cheese are highly nutritious foods for humans and can support a healthful vegetarian diet.

Partially SupportedSaturated fats are anti-inflammatory fats, whereas polyunsaturated fats may not be.

Partially SupportedActivating aging pathways like mTOR, insulin, and IGF-1 is essential for human growth, development, reproduction, vitality, libido, strength, and avoiding frailty.

Partially SupportedDesiccated cow brain, grass-fed liver, and bone marrow may help improve cognitive decline and psychiatric disorders.

Partially SupportedSarcopenia may be prevented by consuming adequate animal foods.

Partially SupportedMeat and organs should be the center of human diets, as they have historically been, and are not to be feared.

Partially SupportedConsistent over-activation of IGF-1 primarily comes from insulin resistance, not from foods signaling abundance like meat, organs, and dairy.

Partially SupportedEating meat and organs along with good sources of carbohydrates can avoid frailty, the number one cause of death.

Partially SupportedReducing animal protein and replacing it with plant protein can lead to increased frailty.

Partially SupportedUnprocessed meat provides improved libido, mental clarity, satiety leading to weight loss, and increased energy and muscle mass.

Partially SupportedReplacing animal proteins with plant proteins for 12 weeks accelerates bone turnover in healthy adults.

Not SupportedThe claim that high animal protein diets increase testosterone, which accelerates aging, is based on flawed reasoning.

Partially SupportedAvoiding insulin resistance involves not over-activating cortisol, maintaining a healthy gut, and avoiding polyunsaturated fatty acids, especially from seed oils.

Not SupportedHigh meat intake is not supported by good evidence to accelerate fundamental aging processes.

Partially SupportedDietary protein intake is associated with lower fracture risk and less sarcopenia, and there is no evidence that animal meat contributes to amyloid accumulation, Alzheimer's, heart failure, or blood vessel aging.

Partially SupportedSarcopenia is a significant predictor of all-cause mortality among older nursing home residents.

Partially SupportedHigh animal protein diets may provide short-term benefits including feeling stronger, having more energy, building muscle, losing weight, improving insulin resistance, and better libido and erections.

Partially SupportedHigh-fat dairy consumption, including butter, raw whole milk, and cheese, is associated with a lower risk of obesity.

Partially SupportedModerate exercise, sunlight exposure, community engagement, and regular medical care contribute to longevity.

Partially SupportedSome individuals report feeling better and improving specific diseases on high animal protein diets.

Partially SupportedPhasic activation of pathways like mTOR, IGF-1, and insulin is essential for health and development and should not be limited.

Not SupportedAdopting vegetarian or semi-vegetarian diets may be harmful for humans due to increased frailty.

Partially SupportedFrailty is not conducive to longevity.

Not SupportedThe absence of organ meats in a vegetarian diet leads to deficiencies in choline, biotin, riboflavin, coenzyme Q10, peptides, and testosterone.

Partially SupportedVegans and vegetarians tend to have higher levels of advanced glycation end products (AGEs) and carboxymethyl-lysine (CML) compared to meat-eaters.

Partially SupportedAndrogens like DHT may be pro-longevity, while estrogen may be harmful for aging.

Not SupportedRestricting calories, protein, and carbohydrates to avoid mTOR activation may lead to a life lacking vitality and strength with questionable lifespan extension evidence.

Not SupportedLiving 14 to 19 years longer by being castrated is not a desirable trade-off for longevity.

Not SupportedThe Rotterdam study's finding that people who eat less meat live longer is suspect due to potential health user bias.

Not SupportedCastration removes multiple hormones including testosterone and estrogen.

Partially SupportedBlood vessel aging is closely linked to polyunsaturated fatty acids found in plant foods and seed oils.

Not SupportedEpidemiology studies linking margarine intake to increased cardiovascular disease risk may be confounded by unhealthy user bias.

Not SupportedThe claim that long-term high animal protein diets accelerate aging and increase the risk of age-related diseases is unsubstantiated by the article's authors.

Partially SupportedIndividuals who consume less meat, drink less, and smoke less are often those who follow mainstream health advice and eat less meat.

Partially SupportedNature's primary concern is reproduction, not an individual's lifespan beyond that point, which explains aging.

Not SupportedMost centenarians do not consume a lot of animal protein, according to the studies referenced.

Partially SupportedSoy protein consumption in chickens is associated with increased aggressive pecking behavior.

Partially SupportedProtein should be obtained from animal foods and organs, as historically consumed.

Partially SupportedReducing intake of pro-inflammatory sugars and refined carbohydrates, such as bread, pasta, potatoes, and rice, can reduce inflammation.

Partially SupportedRats fed soy protein lived longer and were healthier than rats fed whey protein.

Partially SupportedAn animal-based diet avoids the complications of long-term ketosis by including low-toxicity carbohydrates.

Not SupportedPhytochemicals in plants are redundant for hormetic benefits like NRF2 activation and increased glutathione production, as these benefits can be obtained from ancestral human practices such as heat, cold, exercise, sun exposure, and fasting.

Partially SupportedCaloric restriction is only beneficial in animal studies when the animals are fed a poor quality diet.

Not SupportedA diet with significantly reduced animal protein to a vegan level leads to frailty and increased fracture rates.

Not SupportedBodybuilders consuming large amounts of animal protein, growth hormone, and male hormones often die younger.

Partially SupportedIn Asia, men eating the most red meat have the lowest rates of heart disease, and women eating the most red meat have the lowest rates of cancer.

Not SupportedCaloric restriction is harmful for humans eating a healthy diet and can tank hormones, lead to lean muscle mass loss, affect electrolytes, and increase sex hormone-binding globulin.

Not SupportedAnimal protein-rich diets and carnivore diets do not accelerate aging or harm humans.

Not SupportedThe argument that meat and organs contribute equally to increased rates of younger death as human growth hormone and steroids is flawed.

Not SupportedThe claim that no longevity zone exists where people consume high amounts of meat or animal protein is false.

Not SupportedThere is insufficient evidence to conclude that compounds like nitroso compounds, polycyclic aromatic hydrocarbons, or heterocyclic amines in meat are harmful to humans in reasonable doses.

Partially SupportedMany Westerners consume meat with added sugars, high fructose corn syrup, seed oils, and refined flours in processed foods.

Partially SupportedPaul Saladino maintains IGF-1 levels below the average human population, often by half or a full standard deviation, through his diet and exercise regimen.

Not SupportedThe claim that high animal protein diets accelerate aging is based solely on studies of triple transgenic mice models of Alzheimer's disease.

Partially SupportedStrict vegans who do not use synthetic protein powder or anabolic steroids may be sarcopenic and experience bloating and gas.

Partially SupportedVegans and vegetarians have more advanced glycation end products (AGEs) compared to meat-eaters.

Not SupportedLimiting mTOR, drastically lowering insulin, or having no IGF-1 can lead to negative health consequences such as immunologic issues, hormonal imbalances, electrolyte problems, sleep apnea, and sleep issues.

Partially SupportedFor individuals over 65, limiting protein intake may decrease longevity.

Partially SupportedSoy protein and isoflavones consumption in adult monkeys is associated with increased aggression and decreased affiliative behavior.

Partially SupportedHigher intake of soy foods and soy isoflavones is associated with lower sperm concentration in men from an infertility clinic.

Partially SupportedA more plant-based diet, especially vegetarian or vegan, can cause deficiencies and other problems.

Partially SupportedAdequate protein intake, leucine, and postprandial insulin signaling are important for immune function.

Partially SupportedLife expectancy beyond adulthood is a better indicator of chronic disease burden than infant mortality.

Partially SupportedHumans desire to live long, healthy, strong, and vital lives, avoiding frailty.

Partially SupportedEarly baldness can be a symptom of accelerated aging and increases the risk of age-related diseases.

Partially SupportedHigh animal protein intake may cause hair loss by overstimulating growth pathways that deplete hair follicle stem cells.