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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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MTHFR polymorphism: Does Paul take supplements? — Whalespan

Content›Video›MTHFR polymorphism: Does Pau…

MTHFR polymorphism: Does Paul take supplements?

Paul Saladino3m · 2024-04-14

Claims Made

9

Claims Supported

8

Support Rate

89%

Support rate

8 of 9 claims supported

8 supported1 partial / not

Claims from this content

9

✓Well SupportedA recommended intake for organ meats is a few ounces per week, such as half an ounce to a few ounces of liver and a few ounces of heart per week.✓Well SupportedMethylated B vitamin supplements may be beneficial for individuals with MTHFR, COMT, or other methylation cycle polymorphisms.◐Partially SupportedA complete blood count (CBC) assesses white blood cells, red blood cells, and red blood cell size (MCV) to indicate infection, anemia, or specific types of anemia.◐Partially SupportedMethylated B vitamin supplements may not be necessary for individuals without MTHFR gene polymorphisms.Partially Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

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An animal-based diet typically prevents vitamin B12 deficiency, but insufficient intake of egg yolks, heart, or liver may lead to folate deficiency.

◐Partially SupportedGenetic analysis of single nucleotide polymorphisms related to methylation is valuable for understanding individual physiology.

✓Well SupportedCreatine and omega-3 fatty acids are beneficial for mental and physical function.

◐Partially SupportedIron deficiency anemia can cause microcytic red blood cells, while large red blood cells in an anemic individual may indicate folate or B12 deficiency.

◐Partially SupportedA high hematocrit indicates a large oxygen-carrying capacity beneficial for performance.