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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Stop worrying about your blood sugar spikes — Whalespan

Content›Video›Stop worrying about your blo…

Stop worrying about your blood sugar spikes

Paul Saladino7m · 2022-07-25

Claims Made

13

Claims Supported

9

Support Rate

69%

Support rate

9 of 13 claims supported

9 supported4 partial / not

Claims from this content

12

✓Well SupportedConsuming red orange juice for seven days ameliorates endothelial function and reduces inflammation in non-diabetic subjects with increased cardiovascular risk.◐Partially SupportedFructose consumed within a food matrix, such as in fruit, is likely different and potentially beneficial compared to isolated fructose or processed sugars.✓Well SupportedPaul Saladino maintains low hs-CRP, fibrinogen, and fasting insulin, suggesting no excess glycation or endothelial damage despite high carbohydrate intake.✓Well SupportedFructose and glucose in isolation have negative physiological effects, but can have positive effects when consumed within a whole food matrix.

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓Well Supported

Animal models suggest substituting honey for refined carbohydrates protects rats from hypertriglyceridemic and peroxidative effects of fructose.

✓Well SupportedWhen calories are not controlled, low glycemic index foods tend to outperform high glycemic index foods, suggesting fiber content is a key factor.

◐Partially SupportedPostprandial insulin spikes from carbohydrates like fruit or honey are beneficial for electrolyte balance and hormone regulation.

◐Partially SupportedIntervention studies typically find little relationship between glycemic index or load and physiological measures of disease risk.

✕Not SupportedElevated postprandial blood sugar spikes are not necessarily indicative of metabolic dysfunction, and the association between higher blood sugar levels and disease may be due to underlying metabolic issues.

◐Partially SupportedPaul Saladino's hemoglobin A1c is lower than 98% of carnivores, despite consuming 300 grams of carbohydrates on many days.

◐Partially SupportedA moderate natural fructose diet resulted in higher weight loss compared to a low fructose diet, and improvements in metabolic syndrome parameters were associated with both calorie-restricted diets.

◐Partially SupportedProcessed sugar should be avoided, but fruit and honey are not to be feared.