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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
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Saponins & leaky gut — Whalespan

Content›Video›Saponins & leaky gut…

Saponins & leaky gut

Paul Saladino9m · 2023-07-12

Claims Made

26

Claims Supported

9

Support Rate

35%

Support rate

9 of 26 claims supported

9 supported17 partial / not

Claims from this content

18

✕Not SupportedSaponins can inhibit digestive enzymes, cause gut inflammation, leaky gut, and inhibit the digestion of lactose, fats, and proteins.✓Well SupportedSprouting or fermenting grains like oats does not eliminate saponins, and heating does not degrade saponins in oats or quinoa.✕Not SupportedSaponins in oats are difficult to avoid through processing methods like sprouting.✕Not SupportedSaponins have been found to significantly affect growth, feed intake, and reproduction in animals.✕Not Supported

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Saponins increase brush border permeability, potentially enhancing uptake of macromolecules like allergens.

◐Partially SupportedSaponins can impair protein digestion and vitamin/mineral uptake, cause hypoglycemia, and act as anti-fungal and antiviral agents.

◐Partially SupportedCommercial oat products contain significant levels of triterpenoid saponins, ranging from 1.7 to 18.2 micrograms per gram, with oat bran and oatmeal having higher levels than cold oats cereal.

✕Not SupportedQuinoa is not easily digested by humans, leading to poor nutrient absorption.

◐Partially SupportedSaponins increase gut permeability and inhibit active nutrient transport, which is equivalent to leaky gut.

◐Partially SupportedHeating quinoa does not fully remove the damaging effects of saponins on human gastric mucosal cells.

◐Partially SupportedSaponins, like solanine, are plant defense chemicals that can damage the gut, activate the immune system, and lead to inflammation.

✕Not SupportedThe saponins epicatechin A and B, found in oats, may inhibit lactose digestion, leading to lactose intolerance.

◐Partially SupportedSaponins can impair protein digestion and the uptake of vitamins and minerals.

✕Not SupportedSaponins are generally not beneficial for humans.

◐Partially SupportedMany plant-based foods are promoted as healthy without full investigation of their bioactive compounds, which may be problematic for humans.

◐Partially SupportedSaponins can negatively affect animals' reproductive systems, growth, feed intake, and cause hypoglycemia.

✕Not SupportedSaponins cannot be easily washed off or degraded by heating or cooking.

✕Not SupportedSaponins can cause hypoglycemia.