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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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How often bodybuilders use steroids | Peter Attia & Derek MPMD — Whalespan

Content›Video›How often bodybuilders use s…

How often bodybuilders use steroids | Peter Attia & Derek MPMD

Peter Attia11m · 2023-10-14

Claims Made

24

Claims Supported

23

Support Rate

96%

Support rate

23 of 24 claims supported

23 supported1 partial / not

Claims from this content

18

✓Well SupportedTestosterone provides estrogen which offers neuroprotection, especially at physiological levels.✓Well SupportedRecovery of testosterone production is possible in individuals who have used anabolic steroids for five years or longer, though literature is sparse.◐Partially SupportedProgesterone receptor agonism may have an additive effect on breast tissue development alongside estrogen, GH, IGF-1, and prolactin.◐Partially SupportedTo build muscle, individuals typically use a base of testosterone plus one or two anabolic agents, such as primobolan and androne.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Bodybuilders in a calorie deficit may use more anabolic agents to help preserve tissue and support muscle building.

◐Partially SupportedHigh androgenic signaling combined with suppressed estrogen creates negative health factors.

◐Partially SupportedResponding well to anabolic drugs does not necessarily equate to good health.

◐Partially SupportedApproximately 10% of individuals may not resume normal testosterone production after ceasing anabolic-androgenic steroid use.

◐Partially SupportedFitness industry TRT often uses testosterone replacement therapy doses of 200mg or more to bridge between anabolic steroid blast phases.

◐Partially SupportedProfessional bodybuilders are on anabolic steroids 90-100% of the year, having accepted the suppression of endogenous production.

◐Partially SupportedIndividuals prone to gynecomastia may use aggressive dosages of aromatase inhibitors and SERMs to manage androgenic input and prevent estrogenic effects.

◐Partially SupportedBodybuilders may switch to purer anabolics with less water retention during leaning out phases.

◐Partially SupportedBodybuilders taking a month off anabolic steroids is insufficient for recovery as long-acting compounds can take months to clear.

◐Partially SupportedSynthetic estrogen metabolites from some anabolic compounds have less predictable activity at the estrogen receptor compared to natural estrogen.

◐Partially SupportedMany professional bodybuilders proactively undergo surgery for gynecomastia to prevent its development.

◐Partially SupportedUsing HCG throughout anabolic steroid cycles may be important for maintaining testicular volume and easing the transition back to natural recovery.

◐Partially SupportedSynthetic DHT derivatives can compete with testosterone for aromatase, potentially lowering estrogen levels.

◐Partially SupportedThere are likely many undocumented cases of early heart failure in non-famous bodybuilders due to drug use.