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Weekly · Sunday Morning

Five longevity claims.
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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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This Machine Made Me Younger (Insane Results) — Whalespan

Content›Video›This Machine Made Me Younger…

This Machine Made Me Younger (Insane Results)

Bryan Johnson13m · 2025-05-29

Claims Made

36

Claims Supported

26

Support Rate

72%

Support rate

26 of 36 claims supported

26 supported10 partial / not

Claims from this content

23

✓Well SupportedBryan Johnson's telomere length increased by 2.6% after hyperbaric oxygen therapy, equivalent to a decade of aging reversal.✓Well SupportedHyperbaric oxygen therapy resulted in a 2.6% increase in telomere length over 60 sessions for Bryan Johnson.✓Well SupportedStudies suggest hyperbaric oxygen therapy (HBOT) can increase collagen density by 12.8%, elastin elastic fiber length by 144%, and blood vessel count by 41%.✓Well SupportedHyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen inside a pressurized chamber to boost repair and recovery.Well Supported

More from Bryan Johnson

Bryan Johnson's Blueprint Rapamycin Protocol

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Hyperbaric oxygen therapy (HBOT) reduced Bryan Johnson's PALL-127 marker, a specific indicator for Alzheimer's disease, by 28.6%.

◐Partially SupportedHyperbaric oxygen therapy sessions in proximity are more effective than one session per week.

◐Partially SupportedHyperbaric oxygen therapy can increase akkermansia muciniphila levels by 1,000%.

◐Partially SupportedThe dose of hyperbaric oxygen therapy determines its negative effects and longevity benefit.

◐Partially SupportedHyperbaric oxygen therapy (HBOT) may increase VO2Max by approximately 2.46% and VO2AT1 by approximately 6.42% after 21 sessions.

◐Partially SupportedTelomere elongation therapies are promising for longevity.

◐Partially SupportedHyperbaric oxygen therapy increased VEGF levels by 300%, signaling increased blood vessel growth.

?Limited ResearchAfter 60 sessions of hyperbaric oxygen therapy (HBOT) in 90 days, a current thought for optimal continuation dose is 20 sessions every 3 months.

◐Partially SupportedHyperbaric oxygen therapy (HBOT) chambers contain 21% oxygen, allowing for safe use of electronics inside.

◐Partially SupportedCertified hyperbaric oxygen therapy protocols involve baseline measurements, therapy administration, and follow-up measurements.

◐Partially SupportedBlueprint Quantified certifies hyperbaric oxygen therapy clinics using an evidence-based approach with tiered certification levels.

◐Partially SupportedThe fastest depressurization time from two atmospheres in a hyperbaric chamber is around 2 minutes.

◐Partially SupportedA potential protocol for hyperbaric oxygen therapy is 20 sessions every 3 months to stimulate stem cell and VEGF production.

◐Partially SupportedHyperbaric oxygen therapy (HBOT) can be expensive, costing several hundred dollars per session.

◐Partially SupportedThe dose of an intervention determines its longevity benefit.

◐Partially SupportedHyperbaric oxygen therapy involves 90-minute sessions at 2 ATA.

◐Partially SupportedConsult a doctor before hyperbaric oxygen therapy (HBOT) as it may need tailoring to individual health conditions.

◐Partially SupportedHyperbaric oxygen therapy can be challenging due to claustrophobia, breathing resistance, and session duration.

◐Partially SupportedTelomeres are protective caps on chromosomes that shorten with age, linked to cellular aging and age-related diseases.