Audit a URL →

Sign in Sign up free

Loading…

Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

5 audits·1 verdict change·0 affiliate links·Every Sunday

Joining 1,247 readers — founders, MDs, and longevity-obsessed people who fact-check their own health decisions.

Browse

Decisions Claims Content Creators

Product

Audit a URL Sunday roundup API (soon)Pricing

About

FAQ Methodology Editorial Standards Corrections Press & brand RSS feed

Legal

Terms of Service Privacy Policy DMCA

Finally, something serious in this space.
Because we actually read the papers.

© 2026 Whalespan. Independent, evidence-graded longevity.

Plant compounds are a net negative — Whalespan

Content›Video›Plant compounds are a net ne…

Plant compounds are a net negative

Paul Saladino10m · 2022-10-14

Claims Made

22

Claims Supported

11

Support Rate

50%

Support rate

11 of 22 claims supported

11 supported11 partial / not

Claims from this content

21

✕Not SupportedCruciferous vegetables like kale and cauliflower contain goitrogens that can block iodine absorption and negatively impact thyroid function.✕Not SupportedSulforaphane is not considered net beneficial and may be net toxic.✕Not SupportedIsothiocyanates like sulforaphane can inhibit iodine absorption at the thyroid level, which is not beneficial for humans.✓Well SupportedHerbivorous animals have adaptations to plant anti-nutrients, and overconsumption of certain plants can be harmful.Well Supported

Discussion

Native comments, Twitter mentions, and Reddit threads about this content — surfaced together so the conversation isn't fragmented across platforms.

M

Share your read of this content…

Posting publicly as you · linked to your social profiles

Sort by:

AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

High oxalate foods such as spinach, almonds, and turmeric powder may contribute to the development of kidney stones.

✓Well SupportedPlants produce needle-shaped crystals called raphides that can penetrate consumer cells and deliver proteases and soluble oxalate.

◐Partially SupportedIndividuals with Hashimoto's thyroiditis may have fewer oxalate crystals in their thyroid, possibly due to an autoimmune reaction.

✕Not SupportedPlant stems, leaves, roots, and seeds contain defense chemicals that can be harmful to some people.

◐Partially SupportedModern diets high in oxalates can lead to oxalate accumulation and thyroid oxalate crystals.

✓Well SupportedOxalates are a waste byproduct with no known dietary benefit that may inhibit nutrient absorption.

◐Partially SupportedTannins can inhibit protein digestion and reduce protein absorption.

✕Not SupportedSpinach, turmeric, and almonds contain high levels of oxalates, which can contribute to kidney stones and joint issues.

✕Not SupportedFor most individuals with adequate endogenous antioxidant mechanisms, adding vegetables does not enhance antioxidant capacity and may introduce harmful side effects.

✕Not SupportedDaily consumption of spinach is questionable due to its oxalate content, and animal foods like liver offer better nutrient sources.

◐Partially SupportedOxalate has a carcinogenic effect when injected into mouse mammary fat pads, generating malignant fibrosarcoma-like tumors.

◐Partially SupportedPolyphenolic compounds can form insoluble complexes with macromolecules like proteins, reducing protein availability.

◐Partially SupportedOxalates are known to induce breast cancer in animal models by promoting the transformation of breast cells into tumor cells and expressing proto-oncogenes.

✕Not SupportedBroccoli does not provide physiological benefits beyond those achievable through exercise, sauna, cold plunging, fasting, and sunlight.

◐Partially SupportedBroccoli compounds have negative effects in addition to activating Nrf2 and increasing glutathione, unlike environmental stressors like saunas.

◐Partially SupportedOxalic acid and oxalates are generally a waste byproduct for humans, with intake massively increased by consuming certain foods.

✕Not SupportedOxalates found in seeds and beans can accumulate in human tissues and cause health problems.