Paul Saladino· MD
what we're not looking at is like lipid peroxides like 4 h& and acene and we're not looking at thyroid issues with sorane
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
what we're not looking at is like lipid peroxides like 4 h& and acene and we're not looking at thyroid issues with sorane
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my feeling about so for a fame if your listeners haven't heard this is that it's a net negative that if we look at it it may have automatic effects regarding glutathione production but it also competes at the level of the thyroid for part of the floor iodine absorption
sorane is not doing anything in the human body that we cannot do on our own there are other things which can be hermetics and also increase glutathione so chlorophane has no unique mechanism and we know it has toxic effects
sulforaphane has been found to oxidize membrane lipids and damaged DNA directly
in fact I would argue so for a feign it's just going to give you hypothyroidism and probably create more oxidative stress than you need
so for a feign is exactly the same thing it's been shown in studies to decrease DNA damage working through the nrf2 pathway because it's a pro-oxidant and we can talk about hormesis because it's a pro-oxidant and it will increase your glutathione but so for Athene has side effects and nobody talks about these it can compete with i and i on at the level of the thyroid and cause you know thyroid issues for people so for Athene also is known to induce peroxidation of lipid membranes creating for H and E and acrolein
so forth pain circulates in the human body and competes with iodine at the level of the thyroid and can potentially induce thyroid abnormalities
the package in for so insert for so for Athene and all of the isothiocyanates is that they affect iodine at the level of the thyroid they've been shown to damage cell membranes by being Pro oxidants they're creating things like for H and E and they can interfere with this iodine metabolism at the level of the thyroid and do other negative things in terms of oxidative stress in the body other places and they can potentially turn on and off genes in a way that we don't want to happen
so for Athene is known to inhibit iodine absorption at the level of the thyroid Sephora theme is a pro-oxidant it induces lipid peroxidation in the membranes of ourselves
so fluorophane might increase your glutathione but it's also going to circulate in your body along with goitrin and other isothiocyanates that are present in those brassica vegetables and wreak havoc on your thyroid and other hormonal tissues
there are many other bad side effects of sulforaphane as i noted at the level of the thyroid impairing glutathione and recycling etc
the main side effects of this molecule that i have concerns about involve inhibiting the absorption of iodine at the level of the thyroid leading to problems with thyroid hormone synthesis
so sulforaphane for instance will cause nrf2 to turn on genes but it also inhibits iodine absorption at the level of the thyroid dammit
so sulforaphane for instance will cause nrf2 to turn on genes but it also inhibits iodine absorption at the level of the thyroid dammit so if you're trying to recover your thyroid function you want as much thyroid hormone being produced as possible