Audit a URL →

Sign in Sign up free

Loading…

Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

5 audits·1 verdict change·0 affiliate links·Every Sunday

Joining 1,247 readers — founders, MDs, and longevity-obsessed people who fact-check their own health decisions.

Browse

Decisions Claims Content Creators

Product

Audit a URL Sunday roundup API (soon)Pricing

About

FAQ Methodology Editorial Standards Corrections Press & brand RSS feed

Legal

Terms of Service Privacy Policy DMCA

Finally, something serious in this space.
Because we actually read the papers.

© 2026 Whalespan. Independent, evidence-graded longevity.

Hormetic stress: The benefit of SAUNA vs. broccoli — Whalespan

Content›Video›Hormetic stress: The benefit…

Hormetic stress: The benefit of SAUNA vs. broccoli

Paul Saladino16m · 2022-07-22

Claims Made

27

Claims Supported

10

Support Rate

37%

Support rate

10 of 27 claims supported

10 supported17 partial / not

Claims from this content

23

✕Not SupportedSulforaphane may scavenge iodine and act as a goitrogen, with toxic effects.✕Not SupportedSulforaphane is directly toxic to the thyroid gland, inhibiting iodine uptake and thyroid hormone production.◐Partially SupportedA diet with greater than five portions of fruit and vegetables per day for 12 weeks showed no changes in any biomarkers compared to less than two portions.✓Well SupportedCold stress can induce oxidative stress in the human body, similar to molecules like sulforaphane.Well Supported

Discussion

Native comments, Twitter mentions, and Reddit threads about this content — surfaced together so the conversation isn't fragmented across platforms.

M

Share your read of this content…

Posting publicly as you · linked to your social profiles

Sort by:

AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Sulforaphane supplementation, in large amounts, can augment glutathione and influence brain metabolites in human subjects.

◐Partially SupportedSulforaphane from various sources can have side effects.

◐Partially SupportedCompounds in Brassica vegetables can inhibit iodine uptake and should be considered in the context of overall iodine and thyroid health.

✓Well SupportedSulforaphane intake lowered cardiovascular disease risk biomarkers, including oxidized LDL and triglycerides, and reduced the atherogenic index by up to 50%.

✓Well SupportedCertain plant chemicals can be beneficial due to a hormetic effect, similar to sauna exposure.

◐Partially SupportedEnvironmental hormetics like sauna and exercise are a better way to activate antioxidant response genes and stimulate glutathione production compared to molecular hormetics like sulforaphane.

◐Partially SupportedEnvironmental hormesis, including sunlight, exercise, ketosis, fasting, cold exposure, and heat exposure, can increase glutathione levels.

✕Not SupportedThere is no strong evidence that eating vegetables provides benefits beyond those achieved by living a generally healthy lifestyle.

◐Partially SupportedEliminating brassica vegetables from the diet can lead to improvements in gastrointestinal issues, thyroid symptoms, mood, and autoimmune symptoms for many individuals.

✓Well SupportedEnvironmental hormesis, such as from sauna, cold plunge, exercise, and fasting, activates the NRF2 system.

◐Partially SupportedExtracts from cabbage and acidified Brussels sprouts have shown estrogenic effects on a human breast cancer cell line.

◐Partially SupportedHigher doses of sulforaphane may offer benefits beyond those from raw cruciferous vegetables.

◐Partially SupportedSulforaphane levels in broccoli sprouts peak at three milligrams per gram at around 48 hours of growth.

◐Partially SupportedPlant defense chemicals in foods like broccoli may have a hormetic effect.

◐Partially SupportedPlant compounds can activate the NRF2 system but may have uncatalogued side effects similar to pharmaceutical drugs.

✕Not SupportedThe long-term effects of isothiocyanate compounds on humans are not yet fully understood.

◐Partially SupportedCompounds in the brassica family appear to affect humans hormonally, with effects that can vary depending on the dose.

◐Partially SupportedCollards, Brussels sprouts, and some Russian kale contain sufficient goitrin to potentially decrease iodine uptake to the thyroid.

✕Not SupportedThe benefits of sulforaphane from broccoli sprouts or other cruciferous vegetables may be outweighed by their negative side effects, and these benefits can be obtained through environmental hormetic practices like sauna, exercise, sun exposure, and cold plunges.