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The Side Effects of Intermittent Fasting — Whalespan

Content›Video›The Side Effects of Intermit…

The Side Effects of Intermittent Fasting

Paul Saladino7m · 2024-11-12

Claims Made

21

Claims Supported

13

Support Rate

62%

Support rate

13 of 21 claims supported

13 supported8 partial / not

Claims from this content

16

✓Well SupportedPaul Saladino, weighing 165 pounds and exercising over 12 hours/week, consumes 250-300 grams of carbohydrates daily while maintaining insulin sensitivity.✓Well SupportedA cortisol to DHEA ratio below 1.5 was not observed in cancer patients, suggesting a correlation between high cortisol and cancer.✓Well SupportedPaul Saladino remains insulin sensitive despite significant carbohydrate consumption due to his blood work foundation and not being obese or diabetic.✓Well SupportedMeasuring morning fasted cortisol and DHEA levels can help assess the cortisol to DHEA ratio.Partially Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Cortisol is a pro-aging hormone and can reproduce the phenotype of aging when administered at high doses for extended periods.

◐Partially SupportedDoctors should routinely measure fasting insulin and cortisol to DHEA ratio, comparing fasted and afternoon values.

✕Not SupportedExcessive autophagy may lead to negative cardiac remodeling and potentially contribute to precancerous conditions.

◐Partially SupportedIndividuals on a ketogenic diet may experience higher cortisol levels.

◐Partially SupportedFasting insulin tests without a doctor's order are an improvement.

◐Partially SupportedWhen training fasted, Paul Saladino consumes quick-absorbing carbohydrates like watermelon or honey.

✕Not SupportedFasting may induce negative cardiac remodeling or lead to fatty infiltration in cardiac tissues.

✕Not SupportedThe literature on fasting and autophagy is unclear, and autophagy may occur even when eating.

◐Partially SupportedGlucose and trilose can trigger autophagy.

◐Partially SupportedIndividuals should have fasting insulin and cortisol to DHEAS ratios measured at every doctor's visit, ideally in the afternoon and fasted.

◐Partially SupportedThe body should be flexible enough to handle periods without food, but it doesn't need to be a deliberate, constant practice.

◐Partially SupportedFasting can be psychologically beneficial and aid in weight loss for some individuals.