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Weekly · Sunday Morning

Five longevity claims.
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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Will Meat SHORTEN our LIFESPAN? — Whalespan

Content›Video›Will Meat SHORTEN our LIFESP…

Will Meat SHORTEN our LIFESPAN?

Paul Saladino5m · 2020-02-10

Claims Made

12

Claims Supported

10

Support Rate

83%

Support rate

10 of 12 claims supported

10 supported2 partial / not

Claims from this content

12

✓Well SupportedCarnivore dieters report low IGF-1 levels, with fasting levels ranging from 70-90 ng/mL, potentially indicating lower mTOR activation.✓Well SupportedThe body maintains a balance between anabolic and anti-catabolic states, with GH and IGF-1 levels often inversely related.◐Partially SupportedOverstimulation of IGF-1 and mTOR should be avoided.◐Partially SupportedAnimal foods do not necessarily overstimulate IGF-1.◐Partially Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Individuals can optimize their metabolic health by self-testing glucose and ketone levels, and by obtaining blood panels that include IGF-1.

◐Partially SupportedA balance between anabolic and catabolic states is necessary for human health.

◐Partially SupportedThe primary cause of death in modern times is related to diet.

◐Partially SupportedModern civilization faces mortality from chronic diseases related to diet and over-nutrition.

◐Partially SupportedModern Western diets excessively stimulate the anabolic state via mTOR, preventing the body from entering the catabolic state necessary for repair.

◐Partially SupportedThe IGF-1 signaling pathway is necessary for valuable functions in the human body and should not be completely abolished.

◐Partially SupportedChronic over-nutrition and constant mTOR activation prevent cellular repair, leading to diseases of civilization.

◐Partially SupportedConstant eating prevents autophagy by keeping mTOR activated.