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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Sleep loss impairs glucose regulation (but exercise helps) — Whalespan

Content›Video›Sleep loss impairs glucose r…

Sleep loss impairs glucose regulation (but exercise helps)

Rhonda Patrick6m · 2019-03-13

Claims Made

12

Claims Supported

12

Support Rate

100%

Support rate

12 of 12 claims supported

12 supported0 partial / not

Claims from this content

8

✓Well SupportedA single night of 4-hour sleep can decrease insulin sensitivity by up to 25%, leading to worse carbohydrate handling, increased fat storage, and prolonged glucose spikes.✓Well SupportedTwo weeks of restricting sleep to four hours per night reduced glucose uptake into muscle by 50%.✓Well SupportedHIIT, such as hour-long spin classes, can significantly blunt the negative effects of sleep interruption on glucose regulation.✓Well SupportedInsufficient sleep impairs glucose homeostasis by negatively affecting both insulin release from pancreatic beta cells and insulin sensitivity in body cells.

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓Well Supported

Healthy individuals quickly bring down blood sugar spikes after a meal, a process involving cells like muscle cells absorbing glucose, measured by the disposition index.

◐Partially SupportedSleeping less than 7 hours per night is associated with increased fasting insulin, increased glucose levels, elevated HOMA-IR, higher HbA1c, and increased visceral fat.

◐Partially SupportedA glucose tolerance test measures how quickly the body disposes of blood glucose after consuming a glucose drink.

◐Partially SupportedIf good sleep is not possible, engaging in some exercise can help with blood glucose regulation.