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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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The Side Effects of Linoleic Acid on Your Thyroid — Whalespan

Content›Video›The Side Effects of Linoleic…

The Side Effects of Linoleic Acid on Your Thyroid

Paul Saladino6m · 2025-10-08

Claims Made

20

Claims Supported

16

Support Rate

80%

Support rate

16 of 20 claims supported

16 supported4 partial / not

Claims from this content

18

✕Not SupportedHigh doses (4g or more per day) of omega-3 supplementation from fish oil are associated with an increased risk of atrial fibrillation and cardiac arrhythmia.✕Not SupportedFish can contain heavy metals, PFAS, endocrine disruptors, and microplastics, making them a polluted food source.✓Well SupportedThe human body stores consumed polyunsaturated fatty acids, impacting fat cells, membranes, and the brain.✓Well SupportedPolyunsaturated fatty acids may interfere with triiodothyronine binding to thyroid receptors.Well Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Human diets likely evolved to contain about 2% polyunsaturated fatty acids, compared to current intakes of 10-20% or more.

✓Well SupportedFish oil supplements often have a high peroxide index, indicating undesirable oxidation.

✓Well SupportedPolyunsaturated fatty acids can be oxidized when exposed to heat, potentially causing inflammation.

✕Not SupportedMost individuals can obtain sufficient omega-3 fatty acids from dietary sources like egg yolks and grass-fed meat, negating the need for fish oil supplements.

◐Partially SupportedFrequent consumption of fish like tuna can lead to elevated mercury levels.

✓Well SupportedAll foods contain some level of heavy metals, with the concern being the quantity consumed.

◐Partially SupportedElevated heavy metals in the body are linked to physiological problems.

◐Partially SupportedConsuming fish, such as tuna, multiple times per week can lead to elevated mercury levels.

◐Partially SupportedMeat generally contains lower levels of heavy metals than fish, depending on sourcing.

◐Partially SupportedFish consumption carries risks due to heavy metal contamination.

◐Partially SupportedSourcing low heavy metal cacao is possible, as done for Harden Soil's chocolate whey protein.

◐Partially SupportedPaul Saladino's recent heavy metal tests showed low levels of lead, mercury, cadmium, and arsenic, attributed to not eating fish.

◐Partially SupportedThe high modern intake of polyunsaturated fatty acids (PUFAs) represents an evolutionary mismatch, creating health problems for humans.

◐Partially SupportedIncreased incorporation of polyunsaturated fatty acids into mitochondrial membranes creates oxidative stress and membrane dysfunction.