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Rapamycin extends mouse lifespan 9–14%
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Why you need a high VO₂ max — Whalespan

Content›Video›Why you need a high VO₂ max…

Why you need a high VO₂ max

Peter Attia5m · 2024-06-26

Claims Made

10

Claims Supported

10

Support Rate

100%

Support rate

10 of 10 claims supported

10 supported0 partial / not

Claims from this content

7

✓Well SupportedVO2 max is the single most important biomarker for lifespan.✓Well SupportedMaintaining a VO2 max in the mid-20s to high-30s is sufficient to ensure the ability to perform desired daily activities.✓Well SupportedTo maintain a VO2 max of 30 at age 90, one must have a significantly higher VO2 max in midlife, likely in the 95th percentile or above.✓Well SupportedCardiorespiratory fitness, measured by VO2max, declines with age, and maintaining a higher starting level makes this decline less functionally impactful.Partially Supported

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Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

A VO2 max of 50 is required to run at 6 miles per hour up a steep hill.

◐Partially SupportedAchieving a high level of fitness in midlife is necessary to remain unencumbered in the last decade of life.

◐Partially SupportedTraining to improve VO2 max does not require specialized devices, unlike measuring lactate.