Audit a URL →

Sign in Sign up free

Loading…

Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

5 audits·1 verdict change·0 affiliate links·Every Sunday

Joining 1,247 readers — founders, MDs, and longevity-obsessed people who fact-check their own health decisions.

Browse

Decisions Claims Content Creators

Product

Audit a URL Sunday roundup API (soon)Pricing

About

FAQ Methodology Editorial Standards Corrections Press & brand RSS feed

Legal

Terms of Service Privacy Policy DMCA

Finally, something serious in this space.
Because we actually read the papers.

© 2026 Whalespan. Independent, evidence-graded longevity.

Distance running is dangerous — Whalespan

Content›Video›Distance running is dangerou…

Distance running is dangerous

Paul Saladino9m · 2022-08-19

Claims Made

19

Claims Supported

10

Support Rate

53%

Support rate

10 of 19 claims supported

10 supported9 partial / not

Claims from this content

18

✓Well SupportedSulforaphane activates phase 2 detoxification enzymes and deactivates phase 1 enzymes that convert procarcinogens into carcinogens.✓Well SupportedIndividuals with thyroid issues may need to limit cruciferous vegetables like broccoli and kale.✕Not SupportedSulforaphane may scavenge iodine and act as a goitrogen, with toxic effects.✕Not SupportedCruciferous vegetables like kale and cauliflower contain goitrogens that can block iodine absorption and negatively impact thyroid function.Well Supported

Discussion

Native comments, Twitter mentions, and Reddit threads about this content — surfaced together so the conversation isn't fragmented across platforms.

M

Share your read of this content…

Posting publicly as you · linked to your social profiles

Sort by:

AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✓

Exercise, sun exposure, and sauna use are hormetic stressors that lead to beneficial adaptations.

✓Well SupportedThe free testosterone to cortisol ratio is a useful marker for assessing overreaching in athletes and individuals with very low body fat.

✕Not SupportedPeeing blood during ultra-training is a sign of overtraining and indicates a lack of information.

?Limited ResearchHormetic stress, defined as a small dose of a toxin being beneficial, is not well understood in humans, and the optimal amount is unknown.

◐Partially SupportedCortisol pattern disruption can be caused by inadequate nutrients, poor sleep, trauma, heavy metal toxicity, mold toxicity, breast implants, or petrochemical exposure.

◐Partially SupportedIdentify and reduce factors overloading the stress bucket, which may include intense exercise, before addressing 'adrenal dysfunction'.

◐Partially SupportedPhysiology follows hormetic curves, meaning there is an optimal dose for benefit, with too little or too much causing detriment.

◐Partially SupportedA disrupted cortisol pattern, such as a spike in the middle of the night and no rise upon waking, indicates accumulated stress and a need for recovery.

✕Not SupportedDistance running, particularly marathon training, is associated with increased risk of atrial fibrillation and arrhythmogenic right ventricular dysplasia.

◐Partially SupportedBlood sugar can spike due to stress, such as during a heated conversation, even without food intake.

◐Partially SupportedIntense workouts can cause blood sugar spikes, similar to stress responses.

✕Not SupportedExtreme endurance running creates health problems and is not beneficial for humans.

?Limited ResearchThe total amount of hormetic stress an individual can tolerate is not well understood, and exceeding it can lead to negative outcomes.

◐Partially SupportedCortisol pattern disruption is a sign of excessive accumulated stress and inadequate recovery.