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Weekly · Sunday Morning

Five longevity claims.
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Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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I Tried To Make My Face Younger — Whalespan

Content›Video›I Tried To Make My Face Youn…

I Tried To Make My Face Younger

Bryan Johnson10m · 2024-10-10

Claims Made

18

Claims Supported

16

Support Rate

89%

Support rate

16 of 18 claims supported

16 supported2 partial / not

Claims from this content

13

✓Well SupportedBryan Johnson's protocol is at an elite level for biomarkers including testosterone, bone mineral density, and speed of aging.✓Well SupportedBryan Johnson's caloric intake was reduced to 1,950 calories per day, leading to fat loss.◐Partially SupportedLutein intake was reduced from 20 mg to 15 mg daily because it was causing yellow skin.◐Partially SupportedCollagen decreases by approximately 1% per year starting in one's 20s, resulting in a 75% loss by age 80.✕Not Supported

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Bryan Johnson's Blueprint Rapamycin Protocol

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Filler injections under the eyes can mask aging and may migrate, and the preference is for genuine rejuvenation rather than covering up signs of aging.

◐Partially SupportedFacial fat volume significantly impacts perceived youthfulness.

◐Partially SupportedReducing caloric intake by 20% (1950 calories) is valuable for understanding the impact of therapies on lifespan and healthspan.

◐Partially SupportedAutologous Platelet-Rich Fibrin (PRF) under the eyes can help revolumize lost volume and lasts for 3-6 months.

◐Partially SupportedSculptra is a bio-stimulator injected to stimulate natural collagen production for facial rejuvenation.

◐Partially SupportedCaloric restriction, defined as consuming substantially less than 2,500 calories per day to maintain weight, was used as a therapy to slow and reverse aging damage.

✕Not SupportedBryan Johnson discontinued fat transfer for facial rejuvenation due to severe allergic reactions.

◐Partially SupportedA caloric intake of 1,950 calories per day, while achieving good biomarkers, led to constant hunger and discomfort.

◐Partially SupportedBryan Johnson uses two vials of Sculptra every six months, exceeding the recommended dose, to compensate for collagen deficit.