Paul Saladino· MD
it looks to be broken fat cells and this this sort of like impaired adipogenesis like i think insulin resistance most people would agree that insulin resistance aka metabolic dysfunction is starting in the fat cells
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
it looks to be broken fat cells and this this sort of like impaired adipogenesis like i think insulin resistance most people would agree that insulin resistance aka metabolic dysfunction is starting in the fat cells
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the hypothesis is that if fat cells are inappropriately insulin sensitive they just grow and grow and grow grow and grow and then it's a balance right because maybe you have a donut and your fat cells become a little insulin sensitive and then you eat you know organs and meat and things go back but if you're constantly doing this thing where you're eating seed levels because they're good for you bone clothes and they lower your ldl and everybody knows canelo oil is amazing your cardiologist told you it's good for you and everybody knows that saturated fat causes insulin resistance in the fat cell which are you know which isn't a good thing right everybody knows saturated fat causes heart disease and obviously being facetious with all of this then if you continue to do that at some point your fat cells are probably going to pass upon a no return and become a little broken and that seems to be what happens
fat cells that balloon and don't divide are problematic that is when fat cells become disease that's clearly associated with an insulin resistant phenotype
Insulin resistance is impaired adipogenesis, impaired hyperplasia of fat cells.
Yes, broken fat cells cause insulin resistance. If you fix the fat cells and people are still eating the same garbage, they'll get fatter.
I believe that in human physiology, it is very clear that broken fat cells are the cause of insulin resistance, and I'll talk about that in more in a moment.
As I've shown and I'll continue to show, broken fat cells are the cause of insulin resistance, and then I'll talk about how to fix the broken fat cells.
broken fat cells that cannot divide that are forced to expand to become distended and become inflamed are at the root of insulin resistance
adipocyte in diabetic physiology appear to have broken hyperplasia they cannot divide they can only expand they can only hypertrophy and what appears to happen is as these fat cells expand they become distended they release inflammatory meat eaters they release lipokines they become resistant to the signals of insulin and they start releasing free fatty acids all of the time
insulin resistance physiology starts in the fat cell the adipocyte it starts with broken fat cells again look at the podcast on how to lose weight for a deeper dive here but broken fat cells that cannot divide that are forced to expand to become distended and become inflamed are at the root of insulin resistance
broken fat cells that cannot divide that are forced to expand to become distended and become inflamed are at the root of insulin resistance that is diabetic that is metabolic syndrome that is metabolic dysfunction physiology
what causes insulin resistance and I think it's broken fat cells