Inflammation and endotoxins

PS

Paul Saladino9m · 2023-04-12

Claims Made

17

Claims Supported

10

Support Rate

59%

Support rate

10 of 17 claims supported

10 supported7 partial / not

Claims from this content

17

Not SupportedResistant starch found in green bananas, unripe mangoes, and undercooked oats should be avoided by individuals with gut issues or inflammation.Not SupportedPro-inflammatory fats, not carbohydrates, are the primary drivers of obesity and type 2 diabetes.Partially SupportedThe Simaruni tribe, who consume 80% of their calories from starches cooked for at least an hour, have the lowest known incidence of cardiovascular disease.Partially SupportedWhen consuming simple starches, they should always be well-cooked and should not contain resistant starch, as the negative effects of feeding gut bacteria outweigh any benefits of resistant starch.

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A. Volkovreader

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

Partially Supported

Easily digestible starches like white rice and potatoes are unlikely to significantly increase endotoxins because they are absorbed before reaching the colon.

Partially SupportedFoods with medium and high glycemic units are less dangerous in the long run than resistant starches advertised for their low glycemic index.

Partially SupportedHigh basal insulin and high cortisol levels prevent rapid drops in blood glucose, which is critical for brain function.

Partially SupportedWell-cooked starches like brown rice, oats, and certain breads can be part of a healthy diet if prepared properly.

Partially SupportedWell-cooked starches consumed with fat can be tolerated by individuals with a clean small intestine, but others may experience flushing and sweating indicating an endotoxin reaction.

Partially SupportedPolyunsaturated fatty acids (PUFAs) are believed to cause long-term mitochondrial problems contributing to health issues like diabetes.

Not SupportedLow glycemic index foods, particularly starchy and resistant starches, can increase endotoxin levels, inflammation, basal insulin, and cortisol.

Not SupportedProton pump inhibitor drugs can allow bacteria to colonize the small intestine, making starchy foods problematic.

Partially SupportedTraditional populations consuming up to 80% of calories from cooked starches exhibit very low rates of cardiovascular disease.

Partially SupportedActivated charcoal may help retain lean muscle mass and extend lifespan by binding lipopolysaccharide (LPS) and endotoxins in the gut.

Partially SupportedUndigested food entering the colon can increase gram-negative bacteria, leading to increased LPS in the blood and an inflammation cascade.

Partially SupportedDrugs that antagonize the endotoxin receptor TLR4 or serotonin have been shown in animal studies to extend lifespan.

Not SupportedSemi-processed carbohydrates from wheat may contain high levels of phytic acid, which can trigger inflammatory reactions and potentially allergic reactions if it enters the bloodstream.