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Weekly · Sunday Morning

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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Why Thomas DeLauer Quit Keto & Eats Fruit — Whalespan

Content›Video›Why Thomas DeLauer Quit Keto…

Why Thomas DeLauer Quit Keto & Eats Fruit

Paul Saladino10m · 2024-10-16

Claims Made

19

Claims Supported

13

Support Rate

68%

Support rate

13 of 19 claims supported

13 supported6 partial / not

Claims from this content

15

✓Well SupportedBlocking CB1 cannabinoid receptors can reduce hunger and aid weight loss, but may have mood-related side effects.✓Well SupportedSeed oils may disrupt cannabinoid receptors and the hypothalamus, contributing to hunger and obesity.✓Well SupportedFructose from fruit is not significantly harmful to humans and may be a beneficial component of a healthy diet.✓Well SupportedPostprandial insulin spikes from carbohydrates can lead to beneficial changes in sex hormone binding globulin and glutathione.Not Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✕

Calorie-restricted diets can lead to metabolic and hormonal issues and are ineffective for long-term weight loss.

◐Partially SupportedLinoleic acid increases anandamide and 2-arachidonoylglycerol (2-AG) in animal brains, leading to hunger.

◐Partially SupportedOvereating, regardless of macronutrient source, is the primary problem leading to issues like hepatic triglycerides.

◐Partially SupportedTraining intensely in a deep ketogenic state can provide a similar hormetic stressor as extreme caloric deficits.

✕Not SupportedThe demonization of insulin is problematic, as insulin signaling is necessary for various physiological functions.

◐Partially SupportedDrinking ketone esters, ketone salts, or achieving nutritional ketosis in diabetics lowers the hunger hormone ghrelin.

◐Partially SupportedPeriods of ketosis, histone deacetylase inhibition, and being in a ketogenic state are beneficial for humans and mammals.

✕Not SupportedSustainable weight loss requires controlling appetite and feeling satiated, which calorie restriction and 'If It Fits Your Macros' diets fail to achieve.

◐Partially SupportedCutting out seed oils and processed sugars allows for a diet of meat, organs, fruit, and honey without experiencing hunger.

◐Partially SupportedA strict ketogenic or carnivore diet may benefit eczema but could cause other problems.

◐Partially SupportedPostprandial insulin signaling aids kidney sodium and potassium retention, signals liver glutathione production, keeps free sex hormones down, supports normal thyroid hormone levels, and improves athletic recovery.