What damages the gut?

PS

Paul Saladino16m · 2022-07-08

Claims Made

40

Claims Supported

34

Support Rate

85%

Support rate

34 of 40 claims supported

34 supported6 partial / not

Claims from this content

34

Well SupportedSweet pepper extract increases intestinal permeability.Well SupportedPhytohemagglutinin (PHA) from red kidney beans can cause bacterial overgrowth and inflammation by altering the small intestine's mucosal surface.Well SupportedPlant foods, predominantly vegetables, can contain defense chemicals like lectins that may damage the gut.Well SupportedZinc deficiency is linked to increased gut permeability, and zinc from animal foods supports gut barrier integrity.Partially Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

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Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

If an individual is thriving in all aspects of health, there is no need to change their current dietary habits.

Well SupportedZonulin is released in response to gluten exposure in individuals with celiac disease, even in remission, and potentially in non-celiac individuals.

Well SupportedCarrageenan, a thickening agent found in many almond milks, is known to cause gut inflammation and irritation.

Partially SupportedPotato lectin can activate basophils and mast cells, potentially contributing to atopic reactions like eczema, asthma, and allergies.

Partially SupportedLeaky brain is a comorbid condition with leaky gut, suggesting the blood-brain barrier may open similarly to the gastrointestinal epithelium.

Partially SupportedA Westernized diet is often low in fiber and contains seed oils and processed sugars, which can damage the gut.

Well SupportedStevia is a noncaloric sweetener, not an artificial sweetener, and does not appear to negatively impact the gut microbiome.

Partially SupportedOxalates and phytic acid in foods can significantly attenuate or completely abrogate the bioavailability of divalent cations like zinc.

Partially SupportedFish oil (omega-3) can partially rescue omega-6 induced gut dysbiosis but may cause other problems like sepsis.

Not SupportedLimiting carbohydrates for extended periods beyond a few weeks is likely more negative than positive for most humans.

Not SupportedGluten can induce zonulin release and open tight junctions, causing leaky gut, even in individuals without celiac disease.

Partially SupportedHigh glucose or fructose diets can alter gut microbiota and cause metabolic disorders in mice without significant weight change.

Partially SupportedLeaky brain is a comorbid condition with leaky gut, suggesting the blood-brain barrier may open similarly to the gastrointestinal epithelium.

Partially SupportedGalangal, marigold, and hops extracts have been shown to decrease trans-epithelial electrical gradient.

Partially SupportedLectins, found in beans, nuts, grains, and legumes, may contribute to gut dysbiosis and dysmotility by damaging the gut lining and mucus-producing cells.

Partially SupportedSugars from whole food sources like fruit and honey do not cause gut dysbiosis or have the same negative health consequences as processed sugars.

Partially SupportedNon-celiac gluten sensitivity triggers gut dysbiosis, neural inflammation, and gut-brain axis dysfunction, potentially leading to dementia.

Partially SupportedRemoving foods containing lectins, such as wheat, can help with GERD.

Partially SupportedEnvironmental toxins, including trace amounts of jet fuel, car exhaust, and glyphosate in rainwater, contribute to gut dysbiosis.

Partially SupportedIntestinal bacteria, when dysbiotic or overgrown, can open tight junctions.

Partially SupportedDietary emulsifiers like carrageenan, carboxymethyl cellulose, and polysorbate 80 can induce low-grade inflammation and promote colon carcinogenesis.

Partially SupportedA very low carbohydrate diet can improve gastroesophageal reflux symptoms by reducing intake of processed sugars, beans, and grains.

Partially SupportedAntibiotics can damage the gut, leading to dysbiosis.

Partially SupportedCertain bacteria can signal to the gut to open gap junctions and cause leaky gut.

Partially SupportedGluten sensitivity with comorbid diarrhea may persist for decades and is often associated with chronic alcohol consumption, NSAIDs, a fatty diet, and other comorbid disorders.

Partially SupportedGluten fragments like gliadin trigger a danger signal in the gut, opening gap junctions.

Partially SupportedA high glucose or high fructose diet can cause changes in gut microbiota and metabolic disorders in mice.

Partially SupportedGluten is a lectin that can be problematic for both celiac and non-celiac individuals.

Not SupportedExcess omega-6 polyunsaturated fatty acids, such as linoleic acid, cause gut dysbiosis.

Partially SupportedGut dysbiosis and gluten sensitivity can cause gut inflammation and metabolic dysfunction.