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Weekly · Sunday Morning

Five longevity claims.
Worth your time.
Every Sunday.

Last Sunday

Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Not all fats are created equal — Whalespan

Content›Video›Not all fats are created equ…

Not all fats are created equal

Paul Saladino9m · 2022-12-08

Claims Made

25

Claims Supported

19

Support Rate

76%

Support rate

19 of 25 claims supported

19 supported6 partial / not

Claims from this content

23

✓Well SupportedStearic acid ingestion increases circulating C18 triglycerides and activates mitochondrial beta-oxidation.✓Well SupportedSoybean oil consumption increases LPPla2, a particle involved in cleaving oxidized phospholipids in LDL.✓Well SupportedLinoleic acid intake similar to CLA from dairy would likely be harmless due to being an evolutionarily appropriate level.✓Well SupportedEliminating olive oil and focusing on animal fats may help reduce linoleic acid intake and facilitate progress for individuals experiencing weight loss plateaus.Partially Supported

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Peanut, soybean, olive, corn, sunflower, flaxseed, safflower, and rapeseed oils are high in linoleic acid.

◐Partially SupportedPaul Saladino recommends fresh, cold-pressed extra virgin olive oil to his patients.

◐Partially SupportedLinoleic acid is believed to cause weight gain and increase heart disease risk.

◐Partially SupportedIndividuals struggling with weight loss may benefit from eliminating chicken and pork from their diet.

◐Partially SupportedAnimal fats, such as those in 80/20 ground beef and butter, contain beneficial compounds like butyric acid and odd-chain fatty acids.

✕Not SupportedMany olive oils contain a high amount of linoleic acid (7-21%).

◐Partially SupportedFish bioaccumulate contaminants like heavy metals, PFAS, and microplastics more than land animals.

◐Partially SupportedTallow and butter contain a small amount of linoleic acid.

◐Partially SupportedMost people consume 5-10% of their daily calories from linoleic acid, often through 5-7 tablespoons of seed oils per day.

◐Partially SupportedChicken fat from corn and soy-fed animals can increase linoleic acid intake and potentially stall weight loss.

◐Partially SupportedOlive oil may contain excess linoleic acid that could hinder weight loss efforts.

◐Partially SupportedFish is considered a superior food choice compared to processed food and vegetables.

◐Partially SupportedConsuming low-mercury fish like salmon is beneficial, but high intake may require heavy metal testing.

◐Partially SupportedPaul Saladino avoids extra cooking oils, preferring to cook meat on a grill or in pans with minimal added animal fats.

◐Partially SupportedLow-mercury fish like salmon, consumed in moderation, can be beneficial.

◐Partially SupportedSubstituting olive oil for soy oil in energy-restricted programs for obesity treatment can reduce body fat and improve blood pressure.

◐Partially SupportedAnimal fats like tallow and butter may be more beneficial than olive oil in obesity treatment.

◐Partially SupportedGrass-fed and grass-finished beef is preferred.

◐Partially SupportedVegan diets typically lack significant amounts of stearic acid, except for cocoa butter.