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Weekly · Sunday Morning

Five longevity claims.
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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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Are natural sweeteners better? — Whalespan

Content›Video›Are natural sweeteners bette…

Are natural sweeteners better?

Paul Saladino12m · 2023-07-06

Claims Made

24

Claims Supported

14

Support Rate

58%

Support rate

14 of 24 claims supported

14 supported10 partial / not

Claims from this content

23

✓Well SupportedPure fructose or processed sugars like high-fructose corn syrup should not be conflated with whole-food carbohydrate sources such as fruit or honey.✕Not SupportedArtificial sweeteners like stevia, sucralose, and aspartame harm the gut microbiome by interrupting bacterial communication.✓Well SupportedFreshly squeezed red orange juice can be beneficial for the endothelium when consumed in moderation.✓Well SupportedThe relationship between glycemic index, glycemic response, and disease outcomes is limited even in observational studies.Not Supported

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

✕

Artificial sweeteners like stevia in energy drinks can interrupt gut bacteria communication and disrupt the gut microbiome.

✓Well SupportedStudies in mice and rats show high-fructose corn syrup is very different from other carbohydrates.

✓Well SupportedDespite potential blood sugar and insulin spikes, fruit juice consumption is beneficial to humans and supported by significant research.

✓Well SupportedConsuming sugar in whole foods like honey, fruit, or fruit juice does not increase endotoxin levels, lead to insulin resistance, or cause inflammation.

✓Well SupportedIndividuals should tune into their own bodies to understand what dietary and lifestyle choices work best for them, as intuition is key to health.

✓Well SupportedHoney and maple syrup are simpler, more natural sweetener options compared to artificial sweeteners or highly processed natural alternatives.

✓Well SupportedProcessed sugars, particularly from sugar-sweetened beverages, are detrimental to human health.

◐Partially SupportedFactory-farmed meat differs from meat from local farmers who support nose-to-tail nutrition and species-appropriate diets.

◐Partially SupportedHistorically, high fructose corn syrup production could contaminate it with mercury, up to approximately 0.5 micrograms per gram.

✕Not SupportedStevia, erythritol, and monk fruit sweetener can have negative effects in humans.

✕Not SupportedMonk fruit extract may raise insulin levels.

✕Not SupportedSucralose consumed with carbohydrates negatively alters insulin signaling in human studies.

✕Not SupportedAspartame, acek, and sucralose are likely the worst artificial sweeteners.

◐Partially SupportedHigh glycemic index carbohydrates like those in honey and fruit juice are not harmful to humans.

◐Partially SupportedProcessed foods with high fructose corn syrup, binders, wheat gluten, seed oils, and contaminants are problematic for humans.

✕Not SupportedStevia has been used as a contraceptive in indigenous cultures and animal models suggest it can interrupt fertility.

✕Not SupportedAspartame, at doses well below FDA minimums, has been shown in rat studies to cause heritable anxiety for multiple generations.

✕Not SupportedMonk fruit sweetener is problematic due to its concentrated mogrosides, which are not representative of evolutionary human intake.

◐Partially SupportedHigh fructose corn syrup is manufactured from corn through enzymatic processes.